Recombinant Human TIGIT protein, His-Avi-tagged

• Cat.No.: TIGIT-495H
• Product Overview: Recombinant Human TIGIT is expressed from Expi293 with a His tag and Avi Tag at the C-terminal. It contains Met22-Pro141.

Specification

• Description: TIGIT, also called Vstm3, Vsig9, and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins. IGIT is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 16.1kDa. Due to glycosylation, the protein migrates to 20-25kDa based on Bis-Tris PAGE result.
• Protein length: Met22-Pro141
• Endotoxin: Less than 0.1EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE; >95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: TIGIT
• Official Symbol: TIGIT
• Synonyms: TIGIT, VSIG9, VSTM3, WUCAM, T cell immunoreceptor with Ig and ITIM domains
• Gene ID: 201633
• mRNA Refseq: NM_173799.4
• Protein Refseq: NP_776160.2
• MIM: 612859
• UniProt ID: Q495A1