Recombinant Rat Tigit protein, His & T7-tagged
Cat.No. : | Tigit-1441R |
Product Overview : | Recombinant Rat Tigit aa. (Met28~Ser227 (Accession # D3ZTQ2)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Rat |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 25.7kDa |
Protein length : | Met28~Ser227 (Accession # D3ZTQ2) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Isoelectric Point : | 5.4 |
Gene Name : | Tigit T cell immunoreceptor with Ig and ITIM domains [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Tigit |
Synonyms : | Tigit; T cell immunoreceptor with Ig and ITIM domains; RGD1563191; T-cell immunoreceptor with Ig and ITIM domains |
Gene ID : | 363784 |
mRNA Refseq : | XM_017598162.1 |
Protein Refseq : | XP_017453651.1 |
UniProt ID : | D3ZTQ2 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionTIGIT inhibitors are being studied in a range of cancers, including lung cancer, breast cancer, and melanoma, among others.
TIGIT is being explored as a potential target for treating autoimmune diseases by modulating immune responses to prevent excessive inflammation.
TIGIT is being explored as a potential target for cancer immunotherapy, with drugs designed to block TIGIT and enhance the immune system's ability to attack cancer cells.
TIGIT operates as an immune checkpoint, similar to PD-1 and CTLA-4, but it has distinct mechanisms of action and may regulate different aspects of the immune response.
As with any immunotherapy, potential side effects may include immune-related adverse events such as inflammation in various organs, but the specific profile is still under investigation.
Customer Reviews (3)
Write a reviewWith its well-characterized nature and availability in various formats, the TIGIT protein is an advantageous tool that aids researchers in achieving their scientific goals.
Whether it's troubleshooting issues, optimizing experimental protocols, or providing detailed information about the protein, the manufacturer's support team is dedicated to helping researchers overcome any challenges they may encounter.
The manufacturer also ensures that the TIGIT protein is well-characterized, with extensive documentation on its functional properties.
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