Recombinant Human TNFRSF18 Protein, Myc/DDK-tagged, C13 and N15-labeled TNFRSF18-6214H

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Recombinant Human TNFRSF18 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	TNFRSF18-6214H
Product Overview :	TNFRSF18 MS Standard C13 and N15-labeled recombinant protein (NP_004186) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	26 kDa
AA Sequence :	MAQHGAMGAF RALCGLALLC ALSLGQRPTG GPGCGPGRLL LGTGTDARCC RVHTTRCCRD YPGEECCSEW DCMCVQPEFH CGDPCCTTCR HHPCPPGQGV QSQGKFSFGF QCIDCASGTF SGGHEGHCKP WTDCTQFGFL TVFPGNKTHN AVCVPGSPPA EPLGWLTVVL LAVAACVLLL TSAQLGLHIW QLRSQCMWPR ETQLLLEVPP STEDARSCQF PEEERGERSA EEKGRLGDLW VTRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	TNFRSF18 TNF receptor superfamily member 18 [ Homo sapiens (human) ]
Official Symbol :	TNFRSF18
Synonyms :	TNFRSF18; tumor necrosis factor receptor superfamily, member 18; tumor necrosis factor receptor superfamily member 18; AITR; CD357; GITR; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; GITR-D;
Gene ID :	8784
mRNA Refseq :	NM_004195
Protein Refseq :	NP_004186
MIM :	603905
UniProt ID :	Q9Y5U5