Cat.No. :	TNFRSF4-2034H
Product Overview :	Recombinant human TNFRSF4 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description :	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Source :	HEK293
Species :	Human
Tag :	MYC/DDK
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass :	26.6 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name :	TNFRSF4 tumor necrosis factor receptor superfamily, member 4 [ Homo sapiens ]
Official Symbol :	TNFRSF4
Synonyms :	ACT35; CD134; IMD16; OX40; TXGP1L
Gene ID :	7293
mRNA Refseq :	NM_003327
Protein Refseq :	NP_003318
MIM :	600315
UniProt ID :	P43489

Online Inquiry