Recombinant Human TNFRSF4 Protein, Myc/DDK-tagged, C13 and N15-labeled TNFRSF4-4989H

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Recombinant Human TNFRSF4 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	TNFRSF4-4989H
Product Overview :	TNFRSF4 MS Standard C13 and N15-labeled recombinant protein (NP_003318) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	29.3 kDa
AA Sequence :	MCVGARRLGR GPCAALLLLG LGLSTVTGLH CVGDTYPSND RCCHECRPGN GMVSRCSRSQ NTVCRPCGPG FYNDVVSSKP CKPCTWCNLR SGSERKQLCT ATQDTVCRCR AGTQPLDSYK PGVDCAPCPP GHFSPGDNQA CKPWTNCTLA GKHTLQPASN SSDAICEDRD PPATQPQETQ GPPARPITVQ PTEAWPRTSQ GPSTRPVEVP GGRAVAAILG LGLVLGLLGP LAILLALYLL RRDQRLPPDA HKPPGGGSFR TPIQEEQADA HSTLAKITRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	TNFRSF4 TNF receptor superfamily member 4 [ Homo sapiens (human) ]
Official Symbol :	TNFRSF4
Synonyms :	TNFRSF4; tumor necrosis factor receptor superfamily, member 4; TXGP1L; tumor necrosis factor receptor superfamily member 4; ACT35; CD134; OX40; OX40 antigen; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 homologue; OX40L receptor; OX40 cell surface antigen; lymphoid activation antigene ACT35; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor;
Gene ID :	7293
mRNA Refseq :	NM_003327
Protein Refseq :	NP_003318
MIM :	600315
UniProt ID :	P43489