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Recombinant Human TPRKB Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : TPRKB-4205H
Product Overview : TPRKB MS Standard C13 and N15-labeled recombinant protein (NP_057142) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 19.7 kDa
AA Sequence : MQLTHQLDLFPECRVTLLLFKDVKN AGDLRRKAMEGTIDGSLINPTVIVD PFQILVAANKAVHLYKLGKMKTRTL STEIIFNLSPNNNISEALKKFGISA NDTSILIVYIEEGEKQINQEYLISQ VEGHQVSLKNLPEIMNITEVKKIYK LSSQEESIGTLLDAIICRMSTKDVL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : TPRKB TP53RK binding protein [ Homo sapiens (human) ]
Official Symbol : TPRKB
Synonyms : TPRKB; TP53RK binding protein; TP53RK-binding protein; CGI 121; PRPK-binding protein; PRPK (p53-related protein kinase)-binding protein; CGI-121;
Gene ID : 51002
mRNA Refseq : NM_016058
Protein Refseq : NP_057142
MIM : 608680
UniProt ID : Q9Y3C4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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