Recombinant Human TRIM21, GST-tagged
Cat.No. : | TRIM21-106H |
Product Overview : | Human TRIM21 full-length ORF (1 a.a. - 475 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 77.99 kDa |
AA Sequence : | MASAARLTMMWEEVTCPICLDPFVE PVSIECGHSFCQECISQVGKGGGSV CPVCRQRFLLKNLRPNRQLANMVNN LKEISQEAREGTQGERCAV HGERLHLFCEKDGKALCWVCAQSRK HRDHAMVPLEEAAQEYQEKLQVALG ELRRK QELAEKLEVEIAIKRADWKKTVETQ KSRIHAEFVQQKNF LVEEEQRQLQELEKDEREQLRILGE KEAKLAQQSQ ALQELISELDRRCHSSALELLQEVI IVLERSESWNLKDLDITSPELRSVC HVPGLKKML RTCAVHITLDPDTAN PWLILSEDRRQVRLGDTQQSIPGNE ERFDSYPMVLGAQHFHSGKHYWEVD VTGKEAWDLGVCRDSVRRKGHFLLS SKSG FWTIWLWNKQKYEAGTYPQTPLHLQ VPPCQVGIFLDYEAGMVSFYNITDH GSLIYSFSECAFTGPLRPFF SPGFNDGGKNTAPLTLCPLNIGSQG STDY |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | TRIM21 tripartite motif containing 21 [ Homo sapiens (human) ] |
Official Symbol : | TRIM21 |
Synonyms : | TRIM21; SSA; RO52; SSA1; RNF81; tripartite motif containing 21; E3 ubiquitin-protein ligase TRIM21; SS-A; ro(SS-A); 52 kDa Ro protein; RING finger protein 81; Sicca syndrome antigen A; tripartite motif-containing 21; sjoegren syndrome type A antigen; tripartite motif-containing protein 21; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro) |
Gene ID : | 6737 |
mRNA Refseq : | NM_003141 |
Protein Refseq : | NP_003132 |
MIM : | 109092 |
UniProt ID : | P19474 |
Chromosome Location : | 11p15.5 |
Pathway : | Adaptive Immune System; Antigen processing: Ubiquitination & Proteasome degradation; Cytosolic sensors of pathogen-associated DNA |
Function : | DNA binding; RNA binding; ubiquitin-protein ligase activity |
Products Types
◆ Recombinant Protein | ||
TRIM21-2685H | Recombinant Human TRIM21 protein(81-260 aa), C-His-tagged | +Inquiry |
Trim21-6646M | Recombinant Mouse Trim21 Protein, Myc/DDK-tagged | +Inquiry |
TRIM21-4768R | Recombinant Rhesus Macaque TRIM21 Protein, His (Fc)-Avi-tagged | +Inquiry |
TRIM21-671H | Recombinant Human TRIM21 Protein (Met1-Tyr475), His-tagged | +Inquiry |
TRIM21-11H | Recombinant Human TRIM21 Protein (1-475), C-His-tagged | +Inquiry |
◆ Native Protein | ||
TRIM21-212B | Native Cow TRIM21 | +Inquiry |
◆ Lysates | ||
TRIM21-791HCL | Recombinant Human TRIM21 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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