Active Recombinant Human TSLP protein, His-Avi-tagged, Biotinylated

• Cat.No.: TSLP-1391H
• Product Overview: Biotinylated Recombinant Human TSLP protein(Tyr 29 - Gln 159 ), fused with His and Avi tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
• Bio-activity: Immobilized Human TSLP R, Fc Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Human TSLP (R127A, R130A) Protein, His,Avitag with a linear range of 2-31 ng/mL.
• Molecular Mass: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag)The protein has a calculated MW of 18.5 kDa. The protein migrates as 25-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein Length: Tyr 29 - Gln 159
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >90% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
• Storage: For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
  -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: TSLP thymic stromal lymphopoietin [ Homo sapiens ]
• Official Symbol: TSLP
• Synonyms: TSLP; thymic stromal lymphopoietin
• Gene ID: 85480
• mRNA Refseq: NM_033035
• Protein Refseq: NP_149024
• MIM: 607003
• UniProt ID: Q969D9

Reviews

04/04/2019

The TSLP protein offered by the manufacturer excels in its quality and is an excellent match for my experimental requirements.

02/25/2019

Their team of experts is readily available to address any queries or concerns I may have regarding the TSLP protein.

11/22/2016

Their team of experts is readily available to address any concerns or queries I may have regarding the TSLP protein.

Q&As

Can WDR5 play a role in non-cancerous diseases?

Yes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.

How does WDR5 affect neurodevelopment?

WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.

Are there any clinical trials involving WDR5-targeted therapies?

Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.

Is there a connection between WDR5 and autoimmune diseases?

Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.

How can WDR5 be used as a diagnostic marker for cancer?

Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.