|Product Overview :
||Full length Recombinant Human UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1) Protein is produced in Insect Cells and is fused with a His tag at the N-terminal.
||UBA1 (UniProt/Swiss-Prot entry P22314) is catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It activates ubiquitin by adenylating the C-terminal glycine residue with ATP and subsequently linking the adenylated glycine to the side chain of a cysteine residue in E1 thereby forming a ubiquitin-E1 thioester. UBA1 is also required for DNA repair response to replication stress.
||20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
||Purified using FPLC, >95% purity as determined by SDS-PAGE.
||This product is for research use only. Not for use in diagnostic or therapeutic procedures.
||Guaranteed stable for 2 years from date of receipt when stored properly.
||Store at -80 centigrade.
SDS page of the UBA1 recombinant protein. The position of the protein of interest is indicated on the right; the marker (in kDa) is shown on the left.