| Description : |
This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
73.9 kDa |
| AA Sequence : |
MAAGETQLYAKVSNKLKGRSSPSLL EPLLAMGFPVHTALKALAATGRKTA EEALAWLHDHCNDPSLDDPIPQEYA LFLCPTGPLLEKLQEFWRESKRQCA KNRAHEVFPHVTLCDFFTCEDQKVE CLYEALKRAGDRLLGSFPTAVPLAL HSSISYLGFFVSGSPADVIREFAMT FATEASLLAGTSVSRFWIFSQVPGH GPNLRLSNLTRASFVSHYILQKYCS VKPCTKQLHLTLAHKFYPHHQRTLE QLARAIPLGHSCQWTAALYSRDMRF VHYQTLRVLFQYKPQNVDELTLSPG DYIFVDPTQQDEASEGWVIGISQRT GCRGFLPENYTDRASESDTWVKHRM YTFSLATDLNSRKDGEASSRCSGEF LPQTARSLSSLQALQATVARKSVLV VRHGERVDQIFGKAWLQQCSTPDGK YYRPDLNFPCSLPRRSRGIKDFEND PPLSSCGIFQSRIAGDALLDSGIRI SSVFASPALRCVQTAKLILEELKLE KKIKIRVEPGIFEWTKWEAGKTTPT LMSLEELKEANFNIDTDYRPAFPLS ALMPAESYQEYMDRCTASMVQIVNT CPQDTGVILIVSHGSTLDSCTRPLL GLPPRECGDFAQLVRKIPSLGMCFC EENKEEGKWELVNPPVKTLTHGANA AFNWRNWISGNTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
