- Human(12)
- Rat(1)
- Xenopus laevis(1)
Recombinant Human UBE2D2 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | UBE2D2-6315H |
| Product Overview : | UBE2D2 MS Standard C13 and N15-labeled recombinant protein (NP_862821) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 13.5 kDa |
| AA Sequence : | MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE WTQKYAMTRT RPLEQKLISE EDLAANDILD YKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | UBE2D2 ubiquitin-conjugating enzyme E2D 2 [ Homo sapiens (human) ] |
| Official Symbol : | UBE2D2 |
| Synonyms : | UBE2D2; ubiquitin-conjugating enzyme E2D 2; ubiquitin conjugating enzyme E2D 2 (homologous to yeast UBC4/5), ubiquitin conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2 D2; UBC4; UbcH5B; ubiquitin-protein ligase D2; ubiquitin carrier protein D2; ubiquitin-conjugating enzyme E2(17)KB 2; ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); PUBC1; UBC4/5; UBCH5B; E2(17)KB2; |
| Gene ID : | 7322 |
| mRNA Refseq : | NM_181838 |
| Protein Refseq : | NP_862821 |
| MIM : | 602962 |
| UniProt ID : | P62837 |
◆ Recombinant Protein
| UBE2D2-67H | Recombinant Human UBE2D2 Protein | +Inquiry |
| UBE2D2-243H | Recombinant Human UBE2D2 Protein, His-tagged | +Inquiry |
| UBE2D2-71H | Recombinant Human UBE2D2, His-tagged | +Inquiry |
| ube2d2-236X | Recombinant Xenopus ube2d2, His-tagged | +Inquiry |
| UBE2D2-30042TH | Recombinant Human UBE2D2 | +Inquiry |
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◆ Lysates
| UBE2D2-587HCL | Recombinant Human UBE2D2 293 Cell Lysate | +Inquiry |
| UBE2D2-588HCL | Recombinant Human UBE2D2 293 Cell Lysate | +Inquiry |
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UBE2AUBE2BUBE2CUBE2D1UBE2D2UBE2D3UBE2D4UBE2E3UBE2FUBE2G1UBE2HUBE2IUBE2L3UBE2L6UBE2MUBE2NUBE2SUBE2TUBE2V2UBE2E2UBE2G2UBE2Q2UBE2R2UBE3AUBE4AUBE2J1UBE2KUBE2OUBE4BUBE2UUBE2WUBE2V1UBE2Q1UBE2J2UBE2NLUBE2E1UBE2ZUBE3BUBE3CUBE3DUbe1y1UBE2CBPUbe2q2lUBE2QL1Ube2dnl2
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