Active Recombinant Human UBE2E3 Protein, His-tagged

• Cat.No.: UBE2E3-647H
• Product Overview: Recombinant Human UBE2E3 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: UBE2E3 also known as UBCH9 or ubiquitin-conjugating enzyme E2E 3 is a member of the E2 ubiquitin-conjugating enzyme family. UBE2E3 is highly expressed in skeletal muscle. UBE2E3 is essential for the proliferation of RPE-1 cells and is downregulated during RPE layer maturation in the developing mouse eye. These findings indicate that UBE2E3 is a major enzyme in modulating the balance between RPE cell proliferation and differentiation.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
• Bio-activity: 17 nmol/min/mg
• Molecular Mass: 25 kDa
• Purity: >95%
• Applications: Ubiquitin Enzyme Assay, Western Blot
• Stability: 1 year at - 70 centigrade from the date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/ml

Gene Information

• Gene Name: UBE2E3 ubiquitin-conjugating enzyme E2E 3 [ Homo sapiens ]
• Official Symbol: UBE2E3
• Synonyms: UBE2E3; ubiquitin-conjugating enzyme E2E 3; ubiquitin conjugating enzyme E2E 3 (homologous to yeast UBC4/5) , ubiquitin conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2 E3; UbcH9; ubiquitin-protein ligase E3; ubiquitin carrier protein E3; ubiquitin-conjugating enzyme E2-23 kDa; ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5); UBCH9; UbcM2
• Gene ID: 10477
• mRNA Refseq: NM_006357
• Protein Refseq: NP_006348
• MIM: 604151
• UniProt ID: Q969T4