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- Human(9)
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- Rhesus Macaque(1)
Recombinant Human UBE2K Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | UBE2K-4276H |
Product Overview : | UBE2K MS Standard C13 and N15-labeled recombinant protein (NP_005330) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 22.2 kDa |
AA Sequence : | MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA EPDDPQDAVV ANQYKQNPEM FKQTARLWAH VYAGAPVSSP EYTKKIENLC AMGFDRNAVI VALSSKSWDV ETATELLLSN TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | UBE2K ubiquitin-conjugating enzyme E2K [ Homo sapiens (human) ] |
Official Symbol : | UBE2K |
Synonyms : | UBE2K; ubiquitin-conjugating enzyme E2K; HIP2, huntingtin interacting protein 2, ubiquitin conjugating enzyme E2K (UBC1 homolog, yeast); ubiquitin-conjugating enzyme E2 K; HYPG; UBC1; HIP-2; E2(25K); ubiquitin-protein ligase; ubiquitin carrier protein; huntingtin interacting protein 2; huntingtin-interacting protein 2; ubiquitin-conjugating enzyme E2-25K; ubiquitin-conjugating enzyme E2(25K); ubiquitin-conjugating enzyme E2-25 KDA; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast); LIG; HIP2; E2-25K; DKFZp564C1216; DKFZp686J24237; |
Gene ID : | 3093 |
mRNA Refseq : | NM_005339 |
Protein Refseq : | NP_005330 |
MIM : | 602846 |
UniProt ID : | P61086 |
◆ Recombinant Protein
Ube2k-6791M | Recombinant Mouse Ube2k Protein, Myc/DDK-tagged | +Inquiry |
UBE2K-4758H | Recombinant Human UBE2K Protein, GST-tagged | +Inquiry |
UBE2K-208H | Recombinant Human UBE2K protein | +Inquiry |
UBE2K-3537H | Recombinant Human UBE2K, GST-tagged | +Inquiry |
UBE2K-5063R | Recombinant Rhesus monkey UBE2K Protein, His-tagged | +Inquiry |
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◆ Lysates
UBE2K-571HCL | Recombinant Human UBE2K 293 Cell Lysate | +Inquiry |
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UBE2AUBE2BUBE2CUBE2D1UBE2D2UBE2D3UBE2D4UBE2E3UBE2FUBE2G1UBE2HUBE2IUBE2L3UBE2L6UBE2MUBE2NUBE2SUBE2TUBE2V2UBE2E2UBE2G2UBE2Q2UBE2R2UBE3AUBE4AUBE2J1UBE2KUBE2OUBE4BUBE2UUBE2WUBE2V1UBE2Q1UBE2J2UBE2NLUBE2E1UBE2ZUBE3BUBE3CUBE3DUbe1y1UBE2CBPUbe2q2lUBE2QL1Ube2dnl2
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