Recombinant Human UBE2K Protein, Myc/DDK-tagged, C13 and N15-labeled UBE2K-4276H

Recombinant Human UBE2K Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	UBE2K-4276H
Product Overview :	UBE2K MS Standard C13 and N15-labeled recombinant protein (NP_005330) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	22.2 kDa
AA Sequence :	MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA EPDDPQDAVV ANQYKQNPEM FKQTARLWAH VYAGAPVSSP EYTKKIENLC AMGFDRNAVI VALSSKSWDV ETATELLLSN TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	UBE2K ubiquitin-conjugating enzyme E2K [ Homo sapiens (human) ]
Official Symbol :	UBE2K
Synonyms :	UBE2K; ubiquitin-conjugating enzyme E2K; HIP2, huntingtin interacting protein 2, ubiquitin conjugating enzyme E2K (UBC1 homolog, yeast); ubiquitin-conjugating enzyme E2 K; HYPG; UBC1; HIP-2; E2(25K); ubiquitin-protein ligase; ubiquitin carrier protein; huntingtin interacting protein 2; huntingtin-interacting protein 2; ubiquitin-conjugating enzyme E2-25K; ubiquitin-conjugating enzyme E2(25K); ubiquitin-conjugating enzyme E2-25 KDA; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast); LIG; HIP2; E2-25K; DKFZp564C1216; DKFZp686J24237;
Gene ID :	3093
mRNA Refseq :	NM_005339
Protein Refseq :	NP_005330
MIM :	602846
UniProt ID :	P61086