Recombinant Human UGT1A3 Protein, MYC/DDK-tagged UGT1A3-512H

Recombinant Human UGT1A3 Protein, MYC/DDK-tagged

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Recombinant Human UGT1A3 Protein, MYC/DDK-tagged

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Cat.No. : UGT1A3-512H
Product Overview : Recombinant human UGT1A3 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene. [provided by RefSeq, Jul 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 57.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : UDP glucuronosyltransferase family 1 member A3[ Homo sapiens ]
Official Symbol : UGT1A3
Synonyms : UDPGT; UDPGT 1-3; UGT-1C; UGT1-03; UGT1.3; UGT1A3S; UGT1C
Gene ID : 54659
mRNA Refseq : NM_019093.2
Protein Refseq : NP_061966.1
UniProt ID : 606428

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