Recombinant Human UGT1A9 Protein, GST/His-tagged

• Cat.No.: UGT1A9-179H
• Product Overview: Recombinant Human UGT1A9 fused with N-terminal GST and C-terminal His was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Description: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
• Molecular Mass: 85.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 [ Homo sapiens ]
• Official Symbol: UGT1A9
• Synonyms: UGT1A9; UDP glucuronosyltransferase 1 family, polypeptide A9; UDP glycosyltransferase 1 family, polypeptide A9; UDP-glucuronosyltransferase 1-9; HLUGP4; LUGP4; UGT1AI; UDP-glucuronosyltransferase 1-I; UDP-glucuronosyltransferase 1A9; UDPGT; UGT1I; UGT-1I; UGT1-9; UGT1.9; UGT1-09; UDPGT 1-9
• Gene ID: 54600
• mRNA Refseq: NM_021027
• Protein Refseq: NP_066307
• MIM: 606434
• UniProt ID: O60656