Recombinant Human USP14 Protein (Q96-Q494), His tagged
Cat.No. : | USP14-0899H |
Product Overview : | Recombinant Human 6His-TEV-USP14(Q96-Q494 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid |
Protein Length : | Q96-Q494 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 95% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50mM Tris-HCl (pH 7.5), 250mM NaCl, 5% glycerol. |
Shipping : | It is shipped out with blue ice. |
Gene Name : | USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) [ Homo sapiens (human) ] |
Official Symbol : | USP14 |
Synonyms : | USP14; ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase); ubiquitin specific protease 14 (tRNA guanine transglycosylase); ubiquitin carboxyl-terminal hydrolase 14; TGT; ubiquitin thioesterase 14; deubiquitinating enzyme 14; ubiquitin thiolesterase 14; ubiquitin-specific processing protease 14; ubiquitin-specific-processing protease 14; tRNA-guanine transglycosylase, 60-kD subunit; ubiquitin specific protease 14 (tRNA-guanine transglycosylase); |
Gene ID : | 9097 |
mRNA Refseq : | NM_001037334 |
Protein Refseq : | NP_001032411 |
MIM : | 607274 |
UniProt ID : | P54578 |
Products Types
◆ Recombinant Protein | ||
USP14-01H | Active Recombinant Human USP14 Protein | +Inquiry |
USP14-0900H | Recombinant Human USP14 Protein (Q96-Q494), Tag Free | +Inquiry |
Usp14-6865M | Recombinant Mouse Usp14 Protein, Myc/DDK-tagged | +Inquiry |
USP14-4934R | Recombinant Rhesus Macaque USP14 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP14-3617H | Recombinant Human USP14, GST-tagged | +Inquiry |
◆ Lysates | ||
USP14-471HCL | Recombinant Human USP14 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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