Recombinant Human USP20 Protein (K120-V914), Tag Free
Cat.No. : | USP20-0363H |
Product Overview : | Recombinant Human GG-USP20(K120-V914 end) Protein was expressed in Insect cell. |
- Specification
- Gene Information
- Related Products
Description : | Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
Source : | Insect cell |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | K120-V914 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl PH 7.5, 500 mM NaCl, 2 mM DTT, 5% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | USP20 ubiquitin specific peptidase 20 [ Homo sapiens (human) ] |
Official Symbol : | USP20 |
Synonyms : | USP20; ubiquitin specific peptidase 20; ubiquitin specific protease 20; ubiquitin carboxyl-terminal hydrolase 20; KIAA1003; hVDU2; ubiquitin thioesterase 20; deubiquitinating enzyme 20; ubiquitin thiolesterase 20; VHL-interacting deubiquitinating enzyme 2; ubiquitin-specific-processing protease 20; pVHL-interacting deubiquitinating enzyme 2; VDU2; LSFR3A; |
Gene ID : | 10868 |
mRNA Refseq : | NM_001008563 |
Protein Refseq : | NP_001008563 |
UniProt ID : | Q9Y2K6 |
Products Types
◆ Recombinant Protein | ||
USP20-2323H | Recombinant Human USP20 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP20-0364H | Recombinant Human USP20 Protein (K120-V914), GST tagged | +Inquiry |
Usp20-6869M | Recombinant Mouse Usp20 Protein, Myc/DDK-tagged | +Inquiry |
USP20-9952M | Recombinant Mouse USP20 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP20-11221Z | Recombinant Zebrafish USP20 | +Inquiry |
◆ Lysates | ||
USP20-466HCL | Recombinant Human USP20 293 Cell Lysate | +Inquiry |
USP20-467HCL | Recombinant Human USP20 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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