Recombinant Human VPS26A Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: VPS26A-200H
• Product Overview: VPS26A MS Standard C13 and N15-labeled recombinant protein (NP_004887) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38.2 kDa
• AA Sequence: MSFLGGFFGPICEIDIVLNDGETRK MAEMKTEDGKVEKHYLFYDGESVSG KVNLAFKQPGKRLEHQGIRIEFVGQ IELFNDKSNTHEFVNLVKELALPGE LTQSRSYDFEFMQVEKPYESYIGAN VRLRYFLKVTIVRRLTDLVKEYDLI VHQLATYPDVNNSIKMEVGIEDCLH IEFEYNKSKYHLKDVIVGKIYFLLV RIKIQHMELQLIKKEITGIGPSTTT ETETIAKYEIMDGAPVKGESIPIRL FLAGYDPTPTMRDVNKKFSVRYFLN LVLVDEEDRRYFKQQEIILWRKAPE KLRKQRTNFHQRFESPESQASAEQP EMTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: VPS26A vacuolar protein sorting 26 homolog A (S. pombe) [ Homo sapiens (human) ]
• Official Symbol: VPS26A
• Synonyms: VPS26A; vacuolar protein sorting 26 homolog A (S. pombe); vacuolar protein sorting 26 (yeast homolog), vacuolar protein sorting 26 (yeast), vacuolar protein sorting 26 homolog A (yeast), VPS26; vacuolar protein sorting-associated protein 26A; Hbeta58; PEP8A; vesicle protein sorting 26A; HB58; VPS26; FLJ12930
• Gene ID: 9559
• mRNA Refseq: NM_004896
• Protein Refseq: NP_004887
• MIM: 605506
• UniProt ID: O75436