Recombinant Human WDR77 protein, GST-tagged

• Cat.No.: WDR77-318H
• Product Overview: Full-length recombinant human WDR77 protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.
• Source: Insect cell
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
• Molecular Mass: 68 kDa
• Purity: The purity of WDR77 was determined to be >90% by densitometry.
• Applications: Enzyme Assay; WB
• Stability: 1 year at -70 centigrade
• Storage: Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μL

Gene Information

• Gene Name: WD repeat domain 77 [ Homo sapiens (human) ]
• Official Symbol: WDR77
• Synonyms: p44; MEP50; MEP-50; HKMT1069; Nbla10071; p44/Mep50
• Gene ID: 79084
• mRNA Refseq: NM_024102
• Protein Refseq: NP_077007
• MIM: 611734
• UniProt ID: Q9BQA1