Recombinant Full Length Human WDR77 Protein, GST-tagged WDR77-6136HF

Recombinant Full Length Human WDR77 Protein, GST-tagged

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Recombinant Full Length Human WDR77 Protein, GST-tagged

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Cat.No. : WDR77-6136HF Optional Service: Optional requirements on this protein
Product Overview : Human MEP50 full-length ORF ( AAH01679, 1 a.a. - 342 a.a.) recombinant protein with GST-tag at N-terminal.
Description : WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).[supplied by OMIM
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 63.36 kDa
Protein Length : 342 amino acids
AA Sequence : MRKETPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL FKDPCAAPNE GFCSAGVQTE AGVADLTWVG ERGILVASDS GAVELWELDE NETLIVSKFC KYEHDDIVST VSVLSSGTQA VSGSKDICIK VWDLAQQVVL SSYRAHAAQV TCVAASPHKD SVFLSCSEDN RILLWDTRCP KPASQIGCSA PGYLPTSLAW HPQQSEVFVF GDENGTVSLV DTKSTSCVLS SAVHSQCVTG LVFSPHSVPF LASLSEDCSL AVLDSSLSEL FRSQAHRDFV RDATWSPLNH SLLTTVGWDH QVVHHVVPTE PLPAPGPASV TE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : WDR77 WD repeat domain 77 [ Homo sapiens ]
Official Symbol : WDR77
Synonyms : WDR77; WD repeat domain 77; methylosome protein 50; MEP50; androgen receptor cofactor p44; WD repeat-containing protein 77; p44; MEP-50; HKMT1069; Nbla10071; p44/Mep50; MGC2722; RP11-552M11.3;
Gene ID : 79084
mRNA Refseq : NM_024102
Protein Refseq : NP_077007
MIM : 611734
UniProt ID : Q9BQA1
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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