Species : |
Human |
Source : |
E.coli |
Tag : |
Non |
Description : |
14-3-3 gamma (also known as tyrosine 3-monooxygenase/tryp-tophan 5-monooxygenase activation protein, gamma polypeptide) is a member of the 14-3-3 family and is involved in mediating signal transduction by binding to phosphoserine-containing proteins. 14-3-3 gamma can interact with various signaling components including RAF1 and protein kinase C. Various growth factors can induce expression of 14-3-3 gamma in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. Upregulation of 14-3-3 gamma plays a specific protective role in astrocytes under ischemia. Elevation of 14-3-3 gamma protein in astrocytes promotes survival, while a decrease in 14-3-3 gamma enhances apoptosis in astrocytes under ischemia. |
Form : |
50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol |
Molecular Mass : |
29 kDa |
Purity : |
> 85% |
Applications : |
Western Blot |
Stability : |
1 year at -70 centigrade from date of shipment. |
Storage : |
Store product at –70centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : |
0.2 ug/ml |