Recombinant Monkey CD40 Protein, His-tagged, Alexa Fluor 647 conjugated
Cat.No. : | CD40-8824CAF647 |
Product Overview : | Alexa Fluor 647 conjugated recombinant Rhesus CD40(Met 1-Arg193) fused with His tag at C-terminal was expressed in HEK293. |
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Description : | CD40 played an important role in many functions. |
Source : | HEK293 |
Species : | Monkey |
Tag : | His |
Form : | Lyophilized |
Molecular Mass : | 20.7 kDa |
Protein length : | Met1-Arg193, 184 |
N-terminal Sequence Analysis : | Glu 21 |
Endotoxin : | < 1.0 EU/ μg of the protein as determined by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 647 via amines Excitation = 650 nm Emission = 668 nm |
Stability : | Samples are stable for up to 12 months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Reconstitution : | Reconstitute in PBS or others. |
Shipping : | Shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Gene Name : | CD40 CD40 molecule [ Macaca mulatta ] |
Official Symbol : | CD40 |
Synonyms : | tumor necrosis factor receptor superfamily member 5 |
Gene ID : | 707749 |
mRNA Refseq : | NM_001265862 |
Protein Refseq : | NP_001252791 |
Products Types
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCD40 agonists have the potential to enhance immune responses against infectious agents, but their clinical use in this context is an area of ongoing research.
As of my knowledge cutoff date in January 2022, there were no FDA-approved drugs specifically targeting CD40. However, clinical trials were ongoing for CD40-targeted therapies.
Yes, CD40-targeted therapies are often investigated in combination with other treatments like checkpoint inhibitors or chemotherapy to enhance their effectiveness.
Side effects may include flu-like symptoms, cytokine release syndrome, and immune-related adverse events, which can be managed with supportive care and close monitoring.
Research on CD40-targeted therapies for atherosclerosis is still in the experimental stages and not yet in advanced clinical trials.
Customer Reviews (3)
Write a reviewIts utilization in this technique has allowed for precise visualization and determination of protein structures with remarkable clarity and resolution.
The reliable and high-quality results obtained using CD40 protein make it an excellent choice for researchers studying protein structures.
CD40 protein has proved to be an invaluable tool in protein electron microscopy structure analysis.
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