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Recombinant Monkey PDCD1 Protein, Fc-tagged, Alexa Fluor 647 conjugated

Cat.No. : PDCD1-1221RAF647
Product Overview : Alexa Fluor 647 conjugated recombinant rhesus PD1 (NP_001107830.1) (Met1-Gln167) was expressed with the Fc region of human IgG1 at the C-terminus.
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Source : HEK293
Species : Monkey
Tag : Fc
Form : Lyophilized
Molecular Mass : 42.7 kDa
Protein length : 381
N-terminal Sequence Analysis : Leu 25
Endotoxin : < 1.0 EU/ μg of the protein as determined by the LAL method.
Purity : > 85 % as determined by SDS-PAGE
Characteristic : Disulfide-linked homodimer
Labeled with Alexa Fluor 647 via amines
Excitation = 650 nm
Emission = 668 nm
Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 to-70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, pH 7.4, 5%-8% trehalose and mannitol.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name : PDCD1 programmed cell death 1 [ Macaca mulatta ]
Official Symbol : PDCD1
Synonyms : PD1; programmed cell death protein 1
Gene ID : 100135775
mRNA Refseq : NM_001114358
Protein Refseq : NP_001107830

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (14)

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What are the mechanisms by which PDCD1 modulates the immune response to viral infections? 07/31/2022

PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.

What are the mechanisms by which PDCD1 modulates the immune response to viral infections? 11/09/2021

PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.

What role does PDCD1 play in the development of immune tolerance? 10/15/2021

PDCD1 helps develop immune tolerance, preventing overactive immune responses.

How does PDCD1 influence the balance between immune activation and autoimmunity? 05/23/2021

PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.

How does PDCD1 contribute to the exhaustion of T cells in chronic infections and cancer? 08/13/2020

PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.

How does PDCD1 influence the balance between immune activation and autoimmunity? 08/05/2020

PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.

What is the impact of PDCD1 on the effectiveness of immunotherapy in treating cancers? 12/05/2019

PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.

How does PDCD1 contribute to the exhaustion of T cells in chronic infections and cancer? 11/21/2019

PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.

How does PDCD1 (PD-1) regulate immune checkpoint pathways in T cells? 04/24/2019

PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.

What is the impact of PDCD1 on the effectiveness of immunotherapy in treating cancers? 01/19/2019

PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.

What role does PDCD1 play in the development of immune tolerance? 12/08/2018

PDCD1 helps develop immune tolerance, preventing overactive immune responses.

How do alterations in PDCD1 expression or signaling affect autoimmune disease progression? 06/24/2018

Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.

How does PDCD1 (PD-1) regulate immune checkpoint pathways in T cells? 06/24/2018

PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.

How do alterations in PDCD1 expression or signaling affect autoimmune disease progression? 02/06/2018

Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.

Customer Reviews (3)

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Reviews
06/06/2021

    Timely antibody validation, a valuable asset for our laboratory.

    02/12/2021

      Precise protein quantification, fundamental for maintaining data accuracy.

      06/20/2019

        Dependable peptide synthesis, accelerates our peptide-based projects effectively.

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