Recombinant Mouse Abcc1 protein, His & T7-tagged
Cat.No. : | Abcc1-1458M |
Product Overview : | Recombinant Mouse Abcc1 aa. (Arg1219~Ile1469 (Accession # O35379)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein plays an essential role in the defense against toxic compounds and serves as the major high-affinity transporter of leukotriene C4. The encoded protein may also play an essential role in steroid hormone homeostasis as a transporter for steroid hormones and their metabolites. |
Source : | E. coli |
Species : | Mouse |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 31.7kDa. |
Protein length : | Arg1219~Ile1469 (Accession # O35379) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method). |
Purity : | >95% |
Characteristic : | The isoelectric point is 5.9. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Abcc1 |
Synonyms : | MRP; Mrp1; Mdrap; Abcc1a; Abcc1b; ATP-binding cassette, sub-family C (CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1b; LTC4 transporter; leukotriene C(4) transporter; multiple drug resistance-associated protein; multidrug resistance-associated protein 1 |
Gene ID : | 17250 |
mRNA Refseq : | NM_008576.3 |
Protein Refseq : | NP_032602.1 |
UniProt ID : | O35379 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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