Recombinant Mouse Abce1 Protein, Myc/DDK-tagged

• Cat.No.: Abce1-1462M
• Product Overview: Purified recombinant protein of mouse full-length ATP-binding cassette, sub-family E (OABP), member 1 (Abce1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 67.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Abce1 ATP-binding cassette, sub-family E (OABP), member 1 [ Mus musculus (house mouse) ]
• Official Symbol: Abce1
• Synonyms: Abce1; ATP-binding cassette, sub-family E (OABP), member 1; O; R; RLI; Oabp; RNS41; RNS4I; C79080; Rnaseli; ATP-binding cassette sub-family E member 1; ATP-binding cassette, subfamily E, member 1; RNS4l (Eye); RNase L inhibitor; ribonuclease 4 inhibitor; ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor
• Gene ID: 24015
• mRNA Refseq: NM_015751
• Protein Refseq: NP_056566
• UniProt ID: P61222