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Recombinant Mouse Acsm5 Protein, Myc/DDK-tagged

Cat.No. : Acsm5-1512M
Product Overview : Purified recombinant protein of mouse full-length acyl-CoA synthetase medium-chain family member 5 (Acsm5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
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Description : Biased expression in liver adult (RPKM 23.3) and kidney adult (RPKM 20.2)
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 64.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Acsm5 acyl-CoA synthetase medium-chain family member 5 [ Mus musculus (house mouse) ]
Official Symbol : Acsm5
Synonyms : ACSM5; acyl-CoA synthetase medium-chain family member 5; acyl-coenzyme A synthetase ACSM5, mitochondrial; C730019D22; C730027J19Rik
Gene ID : 272428
mRNA Refseq : NM_178758
Protein Refseq : NP_848873
UniProt ID : Q8BGA8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What is the role of ACSM5 in mitochondrial function and biogenesis? 12/17/2022

ACSM5 has been implicated in the regulation of mitochondrial function and biogenesis, particularly in the liver. Studies have suggested that its activity may be involved in the generation of acyl-carnitine derivatives, which can be transported into the mitochondria for further metabolism.

How does ACSM5 participate in intracellular signaling pathways? 10/01/2022

ACSM5 has been shown to participate in intracellular signaling pathways, particularly those involving lipid signaling molecules such as phospholipids and fatty acids. Its activity can affect the production and release of these signaling molecules, which can then activate downstream signaling pathways.

How does ACSM5 activity vary among different tissues and cell types? 03/15/2022

ACSM5 activity has been shown to vary among different tissues and cell types. For example, it is highly expressed in adipose tissue and skeletal muscle, but is relatively low in the liver. Its expression and activity can also be regulated by various factors, including nutritional status and hormonal signaling.

How does ACSM5 affect the bioavailability of drugs and xenobiotics in the body? 10/04/2021

ACSM5 has been shown to play a role in the metabolism of certain drugs and xenobiotics in the body, particularly those containing a carboxyl group. Its activity results in the conversion of these compounds into their corresponding acyl-CoA derivatives, which can be further metabolized or stored in the body. This process can affect the bioavailability and clearance of these compounds in the body.

What is the role of ACSM5 in regulating fatty acid oxidation and lipogenesis? 04/24/2020

ACSM5 has been shown to play a role in both fatty acid oxidation and lipogenesis, depending on the specific substrate and metabolic context. Its activity can affect the balance between these two processes, and may contribute to the dysregulation of lipid metabolism in metabolic disorders such as obesity and diabetes.

What is the involvement of ACSM5 in the development and progression of metabolic disorders such as obesity and diabetes? 12/03/2019

ACSM5 has been implicated in the development and progression of metabolic disorders such as obesity and diabetes. Studies have shown that its expression is increased in adipose tissue in obesity, and that its activity may contribute to the dysregulation of lipid metabolism and insulin sensitivity in these conditions.

How does ACSM5 participate in intracellular signaling pathways? 08/17/2019

ACSM5 has been shown to participate in a number of intracellular signaling pathways involved in cellular growth, survival, and differentiation. For example, ACSM5 has been implicated in the activation of the PI3K/Akt pathway, which regulates cell proliferation and survival in response to growth factors and nutrients. ACSM5 has also been shown to be upregulated by the transcription factor PPARγ, which plays a role in adipogenesis and glucose metabolism. The exact mechanisms by which ACSM5 participates in these pathways are still being elucidated.

What is the effect of ACSM5 deficiency on cellular metabolism and function? 08/10/2019

Animal studies have shown that ACSM5 deficiency can affect cellular metabolism and function, particularly in the liver and skeletal muscle. It has been suggested that this is due to alterations in lipid metabolism and mitochondrial function.

What is the role of ACSM5 in regulating inflammatory processes? 11/20/2018

ACSM5 may play a role in regulating inflammatory processes, particularly in the context of obesity and its associated metabolic disorders. This is thought to be due to its involvement in the metabolism of certain fatty acids and other lipids that are implicated in inflammation.

What is the effect of ACSM5 inhibition on cancer cell growth and survival? 09/06/2018

Recent studies have suggested that ACSM5 inhibition may have anti-tumor effects, particularly in certain types of cancer such as hepatocellular carcinoma. This is thought to be due to alterations in lipid metabolism and mitochondrial function that affect cancer cell growth and survival.

Customer Reviews (5)

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Reviews
09/18/2022

    Affordable, high-quality protein that consistently delivers accurate results. Customer service was exceptional.

    04/23/2022

      It's like a ray of sunshine in our experiments, bringing joy and reliable data. A true delight to work with!

      03/14/2021

        Its high purity and activity have facilitated accurate quantification and precise molecular interactions. It has surpassed my expectations.

        01/19/2021

          The protein's solubility is outstanding. It readily dissolves in our buffers, facilitating hassle-free experimentation and saving us valuable time.

          01/13/2021

            We commend the outstanding attributes of this protein. Its solubility, activity, and consistency have made it an essential tool in our scientific investigations, aiding in the advancement of knowledge.

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