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Recombinant Mouse Adam11 Protein, MYC/DDK-tagged

Cat.No. : Adam11-534M
Product Overview : Purified recombinant protein of full-length mouse a disintegrin and metallopeptidase domain 11 (Adam11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. The protein encoded by this gene is believed to lack metalloproteinase activity due to the lack of a critical catalytic motif. Mice lacking the encoded protein exhibit defects in spatial learning, motor coordination and altered perception of pain. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 84.6 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Adam11 a disintegrin and metallopeptidase domain 11 [ Mus musculus (house mouse) ]
Official Symbol : Adam11
Synonyms : Adam11; a disintegrin and metallopeptidase domain 11; Mdc; AW060611; disintegrin and metalloproteinase domain-containing protein 11; a disintegrin and metalloprotease domain (ADAM) 11; metalloproteinase-like, disintegrin-like, and cysteine-rich protein
Gene ID : 11488
mRNA Refseq : NM_009613
Protein Refseq : NP_033743
UniProt ID : Q9R1V4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (3)

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Where ADAM11 is highly expressed? 08/22/2022

ADAM11 is widely expressed in hippocampus and cerebellum。

Where ADAM11 protein is abundantly expressed in humans? 02/15/2022

ADAM11 is abundantly expressed in the cerebellar cortex and spinal cord, and is also expressed in small amounts in the retina and liver.

Which membrane is recommended for WB of ADAM11 protein? 11/29/2020

You can choose PVDF membranes for western blotting.

Customer Reviews (2)

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Reviews
04/10/2022

    The ADAM11 proteins purchased from your company is suitable for ELISA.

    02/25/2021

      The staff had a good attitude, actively communicated with me and solved many technical problems.

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