| Description : |
This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that is involved in the proteolytic release of membrane-bound proteins in a process called ectodomain shedding. Mice lacking the encoded protein die in utero or fail to survive beyond one week of age. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
63.4 kDa |
| Protein Length : |
827 |
| AA Sequence : |
MRRRLLILTTLVPFVLAPRPPEEAG SGSHPRLEKLDSLLSDYDILSLANI QQHSIRKRDLQSATHLETLLTFSAL KRHFKLYLTSSTERFSQNLRVVVVD GKEESEYSVKWQNFFSGHVVGEPDS RVLAHIGDDDVTVRINTDGAEYNVE PLWRFVNDTKDKRMLVYKSEDIKDF SRLQSPKVCGYLNADSEELLPKGLI DREPSEEFVRRVKRRAEPNPLKNTC KLLVVADHRFYKYMGRGEESTTTNY LIELIDRVDDIYRNTSWDNAGFKGY GVQIEQIRILKSPQEVKPGERHFNM AKSFPNEEKDAWDVKMLLEQFSFDI AEEASKVCLAHLFTYQDFDMGTLGL AYVGSPRANSHGGVCPKAYYNPTVK KNIYLNSGLTSTKNYGKTILTKEAD LVTTHELGHNFGAEHDPDGLAECAP NEDQGGKYVMYPIAVSGDHENNKMF SNCSKQSIYKTIESKAQECFQERSN KVCGNSRVDEGEECDPGIMYLNNDT CCNSDCTLKPGVQCSDRNSPCCKNC QFETAQKKCQEAINATCKGVSYCTG NSSECPPPGDAEDDTVCLDLGKCKA GKCIPFCKREQELESCACVDTDNSC KVCCRNLSGPCVPYVDAEQKNLFLR KGKPCTVGFCDMNGKCEKRVQDVIE RFWDFIDQLSINTFGKFLADNIVGS VLVFSLIFWIPFSILVHCVDKKLDK QYESLSLFHHSNIEMLSSMDSASVR IIKPFPAPQTPGRLQALQPAAMMPP VPAAPKLDHQRMDTIQEDPSTDSHA DDDGFEKDPFPNSSTAAKSFEDLTD HPVTRSEKAASFKLQRQSRVDSKET EC |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
