Recombinant Mouse Adam17 Protein Pre-coupled Magnetic Beads

• Cat.No.: Adam17-308M-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Mouse
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Adam17 a disintegrin andmetallopeptidase domain 17 [ Mus musculus ]
• Official Symbol: Adam17
• Synonyms: Adam17; adisintegrin and metallopeptidase domain 17; Tace; CD156b; disintegrin andmetalloproteinase domain-containing protein 17; ADAM 17; TNF-alphaconvertase; TNF-alpha converting enzyme; EC 3.4.24.86
• Gene ID: 11491
• mRNA Refseq: NM_009615
• Protein Refseq: NP_033745
• UniProt ID: Q3UEC0

Reviews

04/08/2022

Cheap price, high quality products, worth buying again

03/15/2019

The high quality of the purchased protein helped me to obtain satisfactory experimental results.

02/26/2019

Good after-sales service attitude, helped me solve a lot of problems in the experiment.

Q&As

Is ADAM17 protein involved in the renin-angiotensin system?

ADAM17 is a negative regulator of the RAS system.

My research requires high protein purity, can I customize > 90% ADAM17 protein?

Yes, we have produced ADAM17 protein of this purity.

What proteins does ADAM17 cleave?

ADAM17 protein can cleave IL6R, TNFR1, ACE2, etc.

Where ADAM17 is highly expressed?

ADAM17 is widely expressed in somatic and immune cells

In addition to Diabetes mellitus and cardiomyopathy-related research, ADAM17 is currently used in the research of which diseases?

ADAM17 is also currently being used in studies of breast cancer and gastric cancer, etc.

Is ADAM17 associated with the EGFR-PI3K-AKT pathway?

ADAM17 is an activator that mediates the EGFR-PI3K-AKT pathway.

Does the package insert for ADAM17 contain detailed information on the handling of the lyophilized powder product?

The product manual will contain relevant content on product handling, and you can also consult our technical experts on related issues.

ADAM17 protein is also involved in recent activities?

Yes, ADAM17 protein is involved in this promotion.

Does ADAM17 mediate the Notch pathway?

ADAM17 acts as an activator of Notch pathway by mediating the of cleavage of Notch.

Does adding His tag have any effect on protein?

Addition of His tags usually does not affect the function, properties of the target protein.