Recombinant Mouse Adamts4 Protein, Myc/DDK-tagged

• Cat.No.: Adamts4-1530M
• Product Overview: Purified recombinant protein of mouse full-length a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active zinc-dependent aggrecanase enzyme that degrades cartilage.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 91.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Adamts4 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 [ Mus musculus (house mouse) ]
• Official Symbol: Adamts4
• Synonyms: ADAMTS4; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4; A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAMTS-4; ADAM-TS 4; aggrecanase-1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4; ADMP-1; ADAM-TS4; ADAMTS-2; mKIAA0688; 3830423K05
• Gene ID: 240913
• mRNA Refseq: NM_172845
• Protein Refseq: NP_766433
• UniProt ID: Q8BNJ2