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Recombinant Mouse Adamts8 Protein, Myc/DDK-tagged

Cat.No. : Adamts8-1531M
Product Overview : Purified recombinant protein of mouse full-length a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 (Adamts8), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is expressed in mouse lung, heart and macrophage-rich areas of atherosclerotic plaques. The encoded preproprotein undergoes proteolytic processing to generate an active, zinc-dependent aggrecanase enzyme. This gene is located adjacent to a related ADAMTS gene on chromosome 9.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 99.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Adamts8 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 [ Mus musculus (house mouse) ]
Official Symbol : Adamts8
Synonyms : ADAMTS8; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8; A disintegrin and metalloproteinase with thrombospondin motifs 8; ADAM-TS8; ADAM-TS 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAMTS-8 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2); METH2; METH-2
Gene ID : 30806
mRNA Refseq : NM_013906
Protein Refseq : NP_038934
UniProt ID : F8VQ15

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the biological function of ADAMTS8? 07/06/2022

ADAMTS8 shows anti-angiogenesis and inhibition of endothelial cell production

What diseases is ADAMTS8 used to study? 04/07/2022

ADAMTS8 is used in more studies of heart and cardiovascular diseases

What is ADAMTS8 also called? 05/05/2021

ADAMTS8 used to be called METH-2.

Where is ADAMTS8 mainly expressed? 04/10/2021

ADAMTS8 is predominantly expressed in the lungs and heart

What is the structure domain of ADAMTS8? 10/19/2020

Pre-structural domains, metalloproteinase structural domains, disintegrin-like structural domains, central thrombospondin-like motifs, cysteine-rich structural domains, spacer region structural domains and C-terminal motifs

Customer Reviews (3)

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Reviews
06/02/2022

    The technician modified my experimental protocol so that my experiment went smoothly.

    06/15/2021

      Very good after-sales service to get my experiments going!

      01/05/2021

        The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.

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