Recombinant Mouse Adarb1 Protein, MYC/DDK-tagged

• Cat.No.: Adarb1-473M
• Product Overview: Purified recombinant protein of full-length mouse adenosine deaminase, RNA-specific, B1 (Adarb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a double-stranded-RNA-specific adenosine deaminase that is involved in editing pre-mRNAs by site-specific conversion of adenosine (A) to inosine (I). Substrates for this enzyme include ionotropic glutamate receptors (GluR2-6) and serotonin receptor (5HT2C). Studies in rodents have shown that this protein can modify its own pre-mRNA by A->I editing to create a novel acceptor splice site, alternative splicing to which results in down regulation of its protein expression. Additional splicing events result in transcript variants encoding different isoforms.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 78.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Adarb1 adenosine deaminase, RNA-specific, B1 [ Mus musculus (house mouse) ]
• Official Symbol: Adarb1
• Synonyms: Adarb1; adenosine deaminase, RNA-specific, B1; Red1; Adar2; AW124433; AW558573; BB220382; D10Bwg0447e; 1700057H01Rik; double-stranded RNA-specific editase 1; RNA-editing deaminase 1; RNA-editing enzyme 1; dsRNA adenosine deaminase; EC 3.5.4.37
• Gene ID: 110532
• mRNA Refseq: NM_001024837
• Protein Refseq: NP_001020008
• UniProt ID: Q91ZS8