Recombinant Mouse Add2 Protein, MYC/DDK-tagged
Cat.No. : | Add2-540M |
Product Overview : | Purified recombinant protein of full-length mouse adducin 2 (beta), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the beta subunit of the adducin family. Adducins, encoded by alpha, beta and gamma genes, are heteromeric proteins that crosslink actin filaments with spectrin at the cytoskeletal membrane. This protein, primarily found in the brain and hematopoietic cells, is regulated by phosphorylation and calmodulin interactions as it promotes spectrin assembly onto actin filaments, bundles actin and caps barbed ends of actin filaments. In mouse, deficiency of this gene can lead to mild hemolytic anemia and impaired synaptic plasticity. Mutations of this gene in mouse serve as a pathophysiological model for hereditary spherocytosis and hereditary elliptocytosis. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 62.8 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Add2 adducin 2 (beta) [ Mus musculus (house mouse) ] |
Official Symbol : | Add2 |
Synonyms : | Add2; adducin 2 (beta); add97; 2900072M03Rik; beta-adducin; erythrocyte adducin subunit beta; snoRNA MBII-396 |
Gene ID : | 11519 |
mRNA Refseq : | NM_013458 |
Protein Refseq : | NP_038486 |
UniProt ID : | Q9QYB8 |
Products Types
◆ Recombinant Protein | ||
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ADD2-301607H | Recombinant Human ADD2 protein, GST-tagged | +Inquiry |
ADD2-1351M | Recombinant Mouse ADD2 Protein | +Inquiry |
ADD2-337H | Recombinant Human ADD2 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ADD2-9015HCL | Recombinant Human ADD2 293 Cell Lysate | +Inquiry |
ADD2-9016HCL | Recombinant Human ADD2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThere may exist small molecules or drugs that selectively modulate the activity or stability of ADD2.
ADD2 interacts with specific proteins or binding partners, and these interactions can be context-dependent.
The expression profile of ADD2 varies across different tissues and cell types.
ADD2 regulates downstream signaling pathways or target molecules that contribute to its cellular functions.
Specific antibodies or probes can be developed to visualize the localization or dynamics of ADD2 in live cells or tissues.
Post-translational modifications, such as phosphorylation or ubiquitination, occur on ADD2 and can influence its function.
Functional domains or motifs within ADD2 can be identified and characterized.
The expression of ADD2 can be regulated during development or in response to specific stimuli.
Modulating the expression or activity of ADD2 can impact cellular processes like cytoskeletal organization, cell motility, or membrane dynamics.
ADD2 exhibits subcellular localization, and its localization may undergo dynamic changes or translocation.
Customer Reviews (2)
Write a reviewHighly sensitive in bioactivity assays, accurately detecting the activity and concentration of bioactive factors.
Provides accurate and reliable quantification of protein biomarkers in clinical samples.
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