Recombinant Mouse Aunip Protein, Myc/DDK-tagged
Cat.No. : | Aunip-1787M |
Product Overview : | Purified recombinant protein of mouse full-length aurora kinase A and ninein interacting protein (Aunip), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | DNA-binding protein that accumulates at DNA double-strand breaks (DSBs) following DNA damage and promotes DNA resection and homologous recombination. Serves as a sensor of DNA damage: binds DNA with a strong preference for DNA substrates that mimic structures generated at stalled replication forks, and anchors RBBP8/CtIP to DSB sites to promote DNA end resection and ensuing homologous recombination repair. Inhibits non-homologous end joining (NHEJ). Required for the dynamic movement of AURKA at the centrosomes and spindle apparatus during the cell cycle. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 37.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Aunip aurora kinase A and ninein interacting protein [ Mus musculus (house mouse) ] |
Official Symbol : | Aunip |
Synonyms : | Aunip; aurora kinase A and ninein interacting protein; Aunip; Clhc1; 2610002D18Rik; aurora kinase A and ninein-interacting protein; aurora A-binding; clathrin heavy chain linker domain containing 1 |
Gene ID : | 69885 |
mRNA Refseq : | NM_001081099 |
Protein Refseq : | NP_001074568 |
UniProt ID : | E9Q6Z5 |
Products Types
◆ Lysates | ||
AUNIP-8182HCL | Recombinant Human C1orf135 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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