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Recombinant Mouse Bdnf Protein, MYC/DDK-tagged

Cat.No. : Bdnf-703M
Product Overview : Purified recombinant protein of full-length mouse brain derived neurotrophic factor (Bdnf), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the nerve growth factor family. It is involved in the growth, differentiation and survival of specific types of developing neurons both in the central nervous system (CNS) and the peripheral nervous system. It is also involved in regulating synaptic plasticity in the CNS. Expression of a similar gene in human is reduced in both Alzheimer's and Huntington disease patients. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 29.6 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Bdnf brain derived neurotrophic factor [ Mus musculus (house mouse) ]
Official Symbol : Bdnf
Synonyms : Bdnf; brain derived neurotrophic factor; brain-derived neurotrophic factor
Gene ID : 12064
mRNA Refseq : NM_007540
Protein Refseq : NP_031566
UniProt ID : A2AII2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is BDNF measured in clinical settings? 10/26/2021

BDNF levels can be measured through blood tests or cerebrospinal fluid analysis, providing insights into the protein's concentration in the body.

What neurological disorders are associated with BDNF deficiency? 10/03/2018

BDNF deficiency has been linked to conditions such as Alzheimer's disease, Parkinson's disease, and depression.

Are there medications that target BDNF for clinical use? 08/02/2018

While there are no direct BDNF medications, certain drugs and treatments aim to enhance BDNF levels indirectly, offering potential therapeutic benefits.

How does physical exercise influence BDNF levels, and what implications does this have for clinical applications? 06/24/2017

Physical exercise has been shown to increase BDNF production, suggesting that exercise could be used as a non-pharmacological intervention to support neurological health.

What role does BDNF play in synaptic plasticity, and how does it impact learning and memory? 01/28/2016

BDNF is crucial for synaptic plasticity, influencing the strength and efficacy of connections between neurons, which is vital for learning and memory processes.

Customer Reviews (3)

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Reviews
12/31/2022

    The BDNF protein is carefully characterized, and its functional properties are well-documented.

    04/08/2021

      With its high purity and bioactivity, BDNF protein ensures reliable and consistent results in a wide range of experimental applications.

      11/27/2017

        The BDNF protein is of exceptional quality and is perfectly suited to meet the experimental needs of researchers.

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