Recombinant Mouse C8b Protein, MYC/DDK-tagged

• Cat.No.: C8b-469M
• Product Overview: Purified recombinant protein of full-length mouse complement component 8, beta polypeptide (C8b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes the beta subunit of complement component C8 that participates in the assembly of the complement membrane attack complex. The encoded preproprotein undergoes proteolytic processing to generate the beta subunit, which associates with the alpha and gamma subunits to form a trimeric complement component, C8. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. This gene is located adjacent to the gene encoding the alpha subunit.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 66.2 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: C8b complement component 8, beta polypeptide [ Mus musculus (house mouse) ]
• Official Symbol: C8b
• Synonyms: C8b; complement component 8, beta polypeptide; AI595927; 4930439B20Rik; complement component C8 beta chain; complement component 8, beta subunit
• Gene ID: 110382
• mRNA Refseq: NM_133882
• Protein Refseq: NP_598643
• UniProt ID: Q8BH35