Recombinant Mouse Casp3 Protein, MYC/DDK-tagged
Cat.No. : | Casp3-771M |
Product Overview : | Purified recombinant protein of full-length mouse caspase 3 (Casp3), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that belongs to a highly conserved family of cysteinyl aspartate-specific proteases that function as essential regulators of programmed cell death through apoptosis. Members of this family contain an N-terminal pro-domain and require cleavage at specific aspartate residues to become mature. The protein encoded by this gene belongs to a subgroup of cysteinyl aspartate-specific proteases that are activated by initiator caspases and that perform the proteolytic cleavage of apoptotic target proteins. Mice defective for this gene exhibit a variety of phenotypes including reduced neuronal apoptosis resulting in hyperplasias, hearing loss, attenuated osteogenic differentiation of bone marrow stromal stem cells, and pre- and post-natal lethality. Alternative splicing results in multiple transcript variants. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 31.9 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Casp3 caspase 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Casp3 |
Synonyms : | Casp3; caspase 3; CC3; AC-3; Lice; Yama; mldy; CPP32; SCA-1; CASP-3; CPP-32; Caspase-3; A830040C14Rik; caspase-3; SREBP cleavage; activity 1; apopain; caspase 3, apoptosis related cysteine protease; cysteine protease CPP32; protein Yama; EC 3.4.22.56 |
Gene ID : | 12367 |
mRNA Refseq : | NM_009810 |
Protein Refseq : | NP_033940 |
UniProt ID : | P70677 |
Products Types
◆ Recombinant Protein | ||
CASP3-623C | Recombinant Cattle CASP3 Protein, His-tagged | +Inquiry |
CASP3-110C | Recombinant Cynomolgus Monkey CASP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP3-507H | Recombinant Human CASP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP3-01H | Active Recombinant Human CASP3 Protein, His-tagged | +Inquiry |
CASP3-624H | Recombinant Human CASP3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CASP3-7839HCL | Recombinant Human CASP3 293 Cell Lysate | +Inquiry |
CASP3-7838HCL | Recombinant Human CASP3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket