Recombinant Mouse Ccl2 Protein

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Recombinant Mouse Ccl2 Protein

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Cat.No. : Ccl2-2030M
Product Overview : Purified recombinant protein of Mouse chemokine (C-C motif) ligand 2 (Ccl2 / MCP-1) without tag was expressed in HEK293.
Description : This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis.
Source : HEK293
Species : Mouse
Bio-activity : The ED50 is 8 -15 ng/mL, corresponding to a specific activity of 0.6 - 1.25 x 10^5 units/mg, determined by the dose dependent chemoattraction of THP-1 cells.
Molecular Mass : 8.5 kDa
Protein length : Gln24-Arg96
Endotoxin : Less than 0.01 ng/μg protein as determined by the LAL method
Purity : > 98%, as determined by Coomassie stained SDS-PAGE.
Stability : Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Storage : Store at -80 centigrade.
Concentration : Protein formulated and vialed at >50 μg/mL in specified buffer
Storage Buffer : 1 x PBS
SDS-PAGE :

Gene Name : Ccl2 chemokine (C-C motif) ligand 2 [ Mus musculus (house mouse) ]
Official Symbol : Ccl2
Synonyms : Ccl2; chemokine (C-C motif) ligand 2; JE; MCA; MCP; Scy; Sig; HC11; MCAF; MCP-; MCP1; MCP-1; SMC-C; Scya2; Sigje; SMC-CF; AI323594; C-C motif chemokine 2; monocyte chemoattractant protein 1; monocyte chemotactic protein 1; platelet-derived growth factor-inducible protein JE; small-inducible cytokine A2
Gene ID : 20296
mRNA Refseq : NM_011333
Protein Refseq : NP_035463
UniProt ID : P10148
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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