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Recombinant Mouse Ccr7 Protein, MYC/DDK-tagged

Cat.No. : Ccr7-906M
Product Overview : Purified recombinant protein of full-length mouse chemokine (C-C motif) receptor 7 (Ccr7), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
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Description : Biased expression in spleen adult (RPKM 74.8), thymus adult (RPKM 70.1) and 2 other tissues
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 42.9 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ccr7 chemokine (C-C motif) receptor 7 [ Mus musculus (house mouse) ]
Official Symbol : Ccr7
Synonyms : Ccr7; chemokine (C-C motif) receptor 7; EBI1; CCR-7; CD197; Ebi1h; Cdw197; Cmkbr7; CC-CKR-7; C-C chemokine receptor type 7; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; chemokine (C-C) receptor 7; epstein-Barr virus-induced G-protein coupled receptor 1
Gene ID : 12775
mRNA Refseq : NM_007719
Protein Refseq : NP_031745
UniProt ID : P47774

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does CCR7 contribute to lymphocyte trafficking and homing? 01/23/2022

It directs T cells and dendritic cells to lymph nodes, ensuring proper immune surveillance.

What therapeutic strategies are being explored targeting CCR7 for disease treatment? 12/24/2021

Therapeutic strategies include targeting CCR7 to modulate immune responses in autoimmune diseases and cancer.

How is CCR7 implicated in cancer progression and metastasis? 07/08/2021

CCR7 can facilitate tumor cell invasion and metastasis to lymph nodes.

What role does CCR7 play in the formation of immune synapses? 03/15/2021

CCR7 helps form immune synapses for effective T cell activation.

What is the main function of CCR7 in the immune system? 03/01/2021

CCR7 guides the migration of various immune cells to lymphoid tissues, aiding in immune responses.

In which cells or tissues is CCR7 predominantly expressed? 06/27/2020

CCR7 is predominantly expressed in T cells, dendritic cells, and various other immune cells.

Are there known genetic mutations or alterations in CCR7 associated with specific diseases? 07/14/2019

Genetic alterations in CCR7 have been linked to certain autoimmune diseases and cancers.

Customer Reviews (3)

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Reviews
10/16/2022

    Perfect for protein research.

    04/05/2022

      Fast delivery, outstanding product.

      03/14/2022

        Product works as intended.

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