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Recombinant Mouse CD28 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated

Cat.No. : CD28-640MAF488
Product Overview : Alexa Fluor 488 conjugated recombinant Mouse CD28 precursor extracellular domain (Met 1-Lys 149) (NP_031668.3), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell.
Availability October 07, 2024
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Source : HEK293
Species : Mouse
Tag : His&Fc
Form : Lyophilized
Molecular Mass : The recombinant mouse CD28/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 378 amino acids and has a predicted molecular mass of 43 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm CD28/Fc monomer is approximately 55-60 kDa due to glycosylation.
Protein length : 378
Endotoxin : < 1.0 EU/ μg of the protein as determined by the LAL method.
Characteristic : Disulfide-linked homodimer
Labeled with Alexa Fluor 488 via amines
Excitation Wavelength: 488 nm
Emission Wavelength: 515­-545 nm
Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, pH 7.4
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name : Cd28 CD28 antigen [ Mus musculus ]
Official Symbol : CD28
Gene ID : 12487
mRNA Refseq : NM_007642
Protein Refseq : NP_031668

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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08/24/2021

    Its unique characteristics contribute to obtaining clear and detailed structural information, enabling researchers to unravel the intricate complexities of protein interactions and conformational changes.

    08/24/2021

      Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.

      08/06/2021

        the CD28 protein's outstanding performance in ELISA and its utility in protein electron microscopy structure analysis make it a highly recommended tool for researchers.

        Q&As (5)

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        Can CD28 protein be used for personalized medicine? 01/13/2023

        CD28 protein expression and function may be relevant for personalized treatment strategies in autoimmune diseases and cancer.

        What are the potential clinical applications of targeting CD28 protein? 05/18/2021

        Targeting CD28 protein may have therapeutic potential in treating autoimmune diseases, cancer immunotherapy, and organ transplantation.

        How does CD28 protein impact regulatory T cells (Tregs)? 06/21/2019

        CD28 signaling is important for the function and maintenance of regulatory T cells, which play a role in immune tolerance and suppression of autoimmunity.

        How does CD28 protein impact cancer immunotherapy? 11/26/2018

        CD28 protein is involved in enhancing the anti-tumor immune response, making it a potential target for cancer immunotherapy.

        Are there any approved therapies targeting CD28 protein? 05/27/2017

        Currently, there are no FDA-approved therapies specifically targeting CD28 protein, but research is ongoing in this area.

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