Recombinant Mouse CD3E & CD3D protein, hFc-tagged CD3E & CD3D-401M

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Recombinant Mouse CD3E & CD3D protein, hFc-tagged

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Cat.No. :	CD3E & CD3D-401M
Product Overview :	Recombinant Mouse CD3E&CD3D Protein is expressed from mammalian with a hFc Tag at the C-terminal It contains Asp23-Asp108 (P22646) & Phe22-Ala105 (P04235).
Description :	T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
Source :	HEK293
Species :	Mouse
Tag :	hFc
Form :	Supplied as 0. 22um filtered solution in PBS (pH 7. 4).
Molecular Mass :	The protein has a predicted MW of 36. 1 kDa (CD3E )and 35. 2 kDa (CD3D ). Due to glycosylation, the protein migrates to 50-65KDa and 40-50KDa based on Bis-Tris PAGE result.
Protein length :	It contains Asp23-Asp108 (P22646) & Phe22-Ala105 (P04235).
Endotoxin :	Less than 0. 1 EU per ug by the LAL method.
Purity :	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Storage :	The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution :	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :
HPLC data :

Gene Name :	Cd3e CD3 antigen, epsilon polypeptide [ Mus musculus ]
Official Symbol :	CD3E; CD3D
Synonyms :	CD3;CD3D;CD3-DELTA;T3D;CD3E
Gene ID :	12501
mRNA Refseq :	NM_007648
Protein Refseq :	NP_031674
UniProt ID :	P22646