Recombinant Mouse CD40 Protein, Fc-tagged, Alexa Fluor 555 conjugated
Cat.No. : | Cd40-325MAF555 |
Product Overview : | Alexa Fluor 555 conjugated recombinant Mouse Cd40 (NP_035741.2) (Met1-Arg193) was expressed with the Fc region of rabbit IgG at the C-terminus. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. |
Source : | HEK293 |
Species : | Mouse |
Tag : | Fc |
Form : | Lyophilized |
Molecular Mass : | 45.4 kDa |
Protein length : | Met1-Arg193, 405 |
N-terminal Sequence Analysis : | Leu 20 |
Endotoxin : | < 1.0 EU/ μg protein as determined by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 555 via amines With an excitation and emission maximum of 555/565 nm, Alexa Fluor 555 can be efficiently excited using a 543 nm He-Ne laser line and detected under standard TRITC/Cy3 filters. |
Storage : | Samples are stable for up to twelve months from date of receipt at -70 centigrade. Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | Cd40 CD40 antigen [ Mus musculus ] |
Official Symbol : | Cd40 |
Synonyms : | CD40; CD40 antigen; tumor necrosis factor receptor superfamily member 5; CD40L receptor; B-cell surface antigen CD40; T-cell differentiation antigen; tumor necrosis factor receptor superfamily, member 5; IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936; |
Gene ID : | 21939 |
mRNA Refseq : | NM_011611 |
Protein Refseq : | NP_035741 |
Products Types
◆ Recombinant Protein | ||
CD40-816M | Recombinant Mouse CD40 Protein (Val24-Arg193), His-tagged | +Inquiry |
CD40-628H | Recombinant Human CD40 Protein | +Inquiry |
Cd40-8727R | Recombinant Rat Cd40 protein(Met1-Arg193), His-tagged | +Inquiry |
CD40-0811H | Recombinant Human CD40 Protein, His-Flag-StrepII-Tagged | +Inquiry |
CD40-0812H | Recombinant Human CD40 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CD40-2617HCL | Recombinant Human CD40 cell lysate | +Inquiry |
CD40-001CCL | Recombinant Canine CD40 cell lysate | +Inquiry |
CD40-1254CCL | Recombinant Cynomolgus CD40 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket