Recombinant Mouse Cdc16 Protein, Myc/DDK-tagged

• Cat.No.: Cdc16-2072M
• Product Overview: Purified recombinant protein of mouse full-length CDC16 cell division cycle 16 (Cdc16), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 71.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cdc16 CDC16 cell division cycle 16 [ Mus musculus (house mouse) ]
• Official Symbol: Cdc16
• Synonyms: CDC16; CDC16 cell division cycle 16 homolog (S. cerevisiae); cell division cycle protein 16 homolog; cyclosome subunit 6; anaphase-promoting complex subunit 6; APC6; 2700071J12Rik; 2810431D22Rik
• Gene ID: 69957
• mRNA Refseq: NM_027276
• Protein Refseq: NP_081552
• UniProt ID: Q8R349