Recombinant Mouse Clec7a Protein, His-tagged

• Cat.No.: Clec7a-798M
• Product Overview: Recombinant Mouse Clec7a Protein (Arg71-Leu244) with His tag was expressed in E. coli.

Specification

• Description: Predicted to enable (1->3)-beta-D-glucan binding activity and pattern recognition receptor activity. Predicted to be involved in several processes, including phagocytosis, recognition; positive regulation of cytokine production involved in inflammatory response; and response to fungus. Predicted to be active in cell surface. Is expressed in brain; gut; limb; musculature; and ventral grey horn. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Orthologous to human CLEC7A (C-type lectin domain containing 7A).
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 23.6 kDa; Accurate Molecular Mass: 24 kDa
• Protein length: Arg71-Leu244
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Clec7a C-type lectin domain family 7, member a [ Mus musculus (house mouse) ]
• Official Symbol: Clec7a
• Synonyms: CLEC7A; C-type lectin domain family 7, member a; C-type lectin domain family 7 member A; dectin-1; beta-glucan receptor; DC-associated C-type lectin 1; C-type lectin superfamily member 12; dendritic cell-associated C-type lectin 1; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; BGR; beta-GR; Clecsf12
• Gene ID: 56644
• mRNA Refseq: NM_020008
• Protein Refseq: NP_064392
• UniProt ID: Q6QLQ4