Recombinant Mouse Cplx4 Protein, Myc/DDK-tagged

• Cat.No.: Cplx4-2288M
• Product Overview: Purified recombinant protein of mouse full-length complexin 4 (Cplx4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca2+ vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca2+ vesicle release.
• Molecular Mass: 18.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cplx4 complexin 4 [ Mus musculus (house mouse) ]
• Official Symbol: Cplx4
• Synonyms: CPLX4; complexin 4; complexin-4; CPX IV; complexin IV; CPXIV; Gm957; A930004D23Rik
• Gene ID: 225644
• mRNA Refseq: NM_145493
• Protein Refseq: NP_663468
• UniProt ID: Q80WM3