Recombinant Mouse Cry1 Protein, Myc/DDK-tagged

• Cat.No.: Cry1-2323M
• Product Overview: Purified recombinant protein of mouse full-length cryptochrome 1 (photolyase-like) (Cry1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of this gene results in a shortened circadian cycle in complete darkness.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 68.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cry1 cryptochrome 1 (photolyase-like) [ Mus musculus (house mouse) ]
• Official Symbol: Cry1
• Synonyms: Cry1; cryptochrome 1 (photolyase-like); Ph; Phll1; AU020726; AU021000; cryptochrome-1
• Gene ID: 12952
• mRNA Refseq: NM_007771
• Protein Refseq: NP_031797
• UniProt ID: P97784