Recombinant Mouse Ctsl Protein, His-tagged

• Cat.No.: Ctsl-38M
• Product Overview: Recombinant mouse CTSL, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Mouse
• Source: Insect Cells
• Tag: His
• Description: CTSL, also known as cathepsin L1, is a lysosomal cysteine protease expressed in most eukaryotic cells. It plays a major role in intracellular protein catabolism and is potent in degrading collagen, laminin, elastin, as well as alpha-1 protease inhibitor and other structural proteins of basement membranes.
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 36.8kDa (325aa)40-57KDa (SDS-PAGE under reducing conditions.)
• AA Sequence: TPKFDQTFSA EWHQWKSTHR RLYGTNEEEW RRAIWEKNMR MIQLHNGEYS NGQHGFSMEM NAFGDMTNEE FRQVVNGYRH QKHKKGRLFQEPLMLKIPKS VDWREKGCVT PVKNQGQCGS CWAFSASGCL EGQMFLKTGK LISLSEQNLV DCSHAQGNQG CNGGLMDFAF QYIKENGGLDSEESYPYEAK DGSCKYRAEF AVANDTGFVD IPQQEKALMK AVATVGPISV AMDASHPSLQ FYSSGIYYEP NCSSKNLDHG VLLVGYGYEGTDSNKNKYWL VKNSWGSEWG MEGYIKIAKD RDNHCGLATA ASYPVVNLEH HHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Ctsl cathepsin L [ Mus musculus ]
• Official Symbol: Ctsl
• Synonyms: Cathepsin L1; CTSL; CatL; Ctsl1; fs; MEP; nkt
• Gene ID: 13039
• mRNA Refseq: NM_009984
• Protein Refseq: NP_034114
• UniProt ID: P06797
• Chromosome Location: 13 B3; 13 33.26 cM
• Pathway: Antigen processing and presentation, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; PodNet: protein-protein interactions in the podocyte, organism-specific biosystem
• Function: aminopeptidase activity; cysteine-type carboxypeptidase activity; histone binding