"CXCL10" Related Products

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Recombinant Mouse CXCL10 Protein (Ile22-Pro98), His-tagged

Cat.No.: CXCL10-805M
Product Overview: Recombinant Mouse CXCL10 Protein (NP_067249.1) (Ile22-Pro98) was produced by Yeast expression system. This protein was expressed with a polyhistidine tag at the C-terminus.
Description: (C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.
Source: Yeast
Species: Mouse
Tag : His
Predicted N Terminal: Ile 22
Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass: The recombinant mouse CXCL10 consists of 87 amino acids and predicts a molecular mass of 10.1 kDa.
Protein length: Ile22-Pro98
Purity: > 90 % as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage: Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name: Cxcl10 chemokine (C-X-C motif) ligand 10 [ Mus musculus ]
Official Symbol: CXCL10
Synonyms: CXCL10; gamma-IP10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10;
Gene ID: 15945
mRNA Refseq: NM_021274
Protein Refseq: NP_067249
UniProt ID: P17515

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