Recombinant Mouse CXCL9 (MIG) CXCL9-73M

Recombinant Mouse CXCL9 (MIG)

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Cat.No. : CXCL9-73M Optional Service: Optional requirements on this protein
Product Overview : Mouse CXCL9/MIG was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
Description : Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family. It is also commonly known as Monokine Induced by Gamma interferon (MIG). CXCL9 (MIG) is a T-cell chemoattractant, which is induced by IFN-gamma. It is closely related to two other CXC chemokines -CXCL10 and CXCL11. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3.
Source : Yeast
Species : Mouse
Form : Lyophilized
Molecular Mass : 12.2 kDa
AA Sequence : TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT (105)
Applications : The mouse CXCL9/MIG protein can be used in cell culture, as a CXCL9/MIG ELISA Standard, and as a Western Blot Control.
Storage : -20 C
Gene Name : Cxcl9 chemokine (C-X-C motif) ligand 9 [ Mus musculus ]
Official Symbol : CXCL9
Synonyms : CXCL9; chemokine (C-X-C motif) ligand 9; C-X-C motif chemokine 9; M119; protein m119; small-inducible cytokine B9; gamma interferon-induced monokine; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; small inducible cytokine B subfamily (Cys-X-Cys), member 9; CMK; Mig; MuMIG; Scyb9; crg-10; BB139920;
Gene ID : 17329
mRNA Refseq : NM_008599
Protein Refseq : NP_032625
Pathway : Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem;
Function : cytokine activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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