Recombinant Mouse Dck Protein, Myc/DDK-tagged
Cat.No. : | Dck-2472M |
Product Overview : | Purified recombinant protein of mouse full-length deoxycytidine kinase (Dck), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 30.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Dck deoxycytidine kinase [ Mus musculus (house mouse) ] |
Official Symbol : | Dck |
Synonyms : | DCK; deoxycytidine kinase |
Gene ID : | 13178 |
mRNA Refseq : | NM_007832 |
Protein Refseq : | NP_031858 |
UniProt ID : | P43346 |
Products Types
◆ Recombinant Protein | ||
DCK-1451R | Recombinant Rat DCK Protein, His (Fc)-Avi-tagged | +Inquiry |
DCK-2231M | Recombinant Mouse DCK Protein, His (Fc)-Avi-tagged | +Inquiry |
DCK-2390H | Recombinant Human DCK Protein, GST-tagged | +Inquiry |
DCK-1016R | Recombinant Rhesus Macaque DCK Protein, His (Fc)-Avi-tagged | +Inquiry |
DCK-0824H | Recombinant Human DCK Protein (M1-L260), Tag Free | +Inquiry |
◆ Lysates | ||
DCK-7051HCL | Recombinant Human DCK 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0879 | dCK Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionReduced DCK activity or expression can lead to resistance against nucleoside analog-based chemotherapy.
Strategies include modulating DCK levels to overcome drug resistance and improve treatment outcomes.
DCK activation of prodrugs enhances their cytotoxicity, improving chemotherapeutic efficacy.
Genetic variants in DCK have been linked to varied responses to nucleoside analog drugs.
It phosphorylates deoxyribonucleosides, contributing to their conversion to active triphosphate forms.
DCK is widely expressed but shows higher activity in proliferating cells and certain tissues like the liver.
DCK plays a crucial role in activating nucleoside analog prodrugs.
Customer Reviews (3)
Write a reviewWorked as expected, pure.
Excellent for research, quality.
Fast shipping, reliable product.
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